To examine whether serial casting promotes autonomic nervous system adaptation in children with spastic CP, in comparison to ankle-foot orthoses (AFOs) and no intervention. Thirty children with spastic CP (aged 6–12…
Neuronal polarization is essential for functional compartmentalization, enabling dendritic synaptic integration and axonal action potential generation. Although structural differences in mitochondria across compartments…
Reshaping cortical circuits through stimulation represents an emerging therapy for the restoration of cognitive function1â5, yet the biological mechanisms that underlie its effects remain largely unexplored in humans…
G-protein-coupled receptor-based fluorescent sensors are widely used to correlate neuromodulatory signaling with brain function. Although experiments in transfected cells often reveal selectivity for individual…
Spontaneous biological oscillations are typically attributed to specific architectures within metabolic or gene regulatory networks. Here, we uncover a more general mechanism arising from the interplay between cellular…
Psychological stress is a major precipitating factor for neuropsychiatric disorders, and the gut-brain axis has emerged as a critical regulator of mood and behavior, but how specific commensal microbes modulate host…
Understanding how adverse life events trigger stress-related behavioural changes remains an unresolved challenge. The amygdala is integral to emotion and stress responses1 and comprises astrocytes, neurons and other…
Brains extract relations between objects and concepts and integrate them into cognitive maps for decision-making. But it remains unclear how they achieve that. Here we present a rigorous theory showing that single…
Human social interaction emerges through coordinated behavior, emotion, and physiology. Biobehavioral synchrony supports stress regulation, attachment, and socio-emotional development, yet its manifestation in…
In the past, cognitive illusions, such as the repetition-based illusory truth and certainty effects, were primarily studied in experimental settings that were far removed from real-world conditions. However, information…
Transcranial focused ultrasound stimulation (tFUS) is an emerging non-invasive neuromodulation technique with unique advantages in targeting deep brain structures with high precision. In this study, we investigated the…
A team of scientists who carried out significant research on the causes of dementia have named three things to avoid. Researchers at NYU Langone Health in the US studied more than 12,000 people to ...
A trove of recent articles bemoan the collapse in recreational reading among younger Americans, with COVID-related reading declines, artificial intelligence and social media often described as causes.
The number of Australians with dementia is forecast to more than double in the next 40 years to almost 1.1 million people, most of them women.
Workplace exposure to pesticides (herbicides and insecticides) is linked to a 60%–70% heightened risk of the most common form of motor neuron disease—amyotrophic lateral sclerosis, or ALS for short—finds a synthesis of…
IBC-Ab002, an anti-PD-L1 immunotherapy targeting systemic immune aging, is safe and reduces markers of neuronal damage in Alzheimer's patients.
A study published in the Journal of Political Economy provides the first causal evidence that improving sleep can directly enhance academic performance.
Eating less sugar during pregnancy and a child's first two years may support long-term brain health and significantly lower the risk of developing dementia later in life.
Ears are built to listen to sounds from the world around us, but for some people, the sound comes from within. Tinnitus causes people to hear ringing or other noises in one or both ears or in their heads, even when there…
Sudden, hard-to-explain market gyrations involving billions of dollars are often triggered by a lack of transparency, new academic research suggests.
A new study using PET imaging reveals that 65% of patients with late-onset psychosis exhibit tau protein buildup in the brain, linking midlife hallucinations and delusions to underlying neurodegeneration.
Physical activity and controlling blood sugar in midlife are associated with a significantly slower rate of cognitive decline later in life, with exercise particularly beneficial for Hispanics, new research from UT…
British swimmer Archie Goodburn's emotional brain cancer plea highlights the urgent need for increased research funding, better treatments, and clinical trial access.
Some speed-reading advocates claim that with proper training (outlined in many popular books and YouTube videos) or the use of special apps, it's possible to increase your reading rate to 1,000 words per minute or more.
A new study shows that strong family, school, and community bonds significantly lower suicide risk, with family attachment reducing risk by one-third.
Australians have seen a flurry of headlines announcing the arrival of blood tests for Alzheimer's disease.
How can Alzheimer's research be made faster, better and more effective? After decades of intensive research worldwide and despite recent therapeutic advances, scientists have not managed to fully arrest the progress of…
It may seem natural to assume that people experience cognitive decline after age 90, but until recently, researchers had limited evidence about how advanced age affects the brain.
Researchers developed a 3D human brain tissue model incorporating neurons, astrocytes, and microglia that replicates Alzheimer's plaque clearance, paving the way for automated high-throughput drug testing.
Nutrition strategies for concussion management are being implemented by dietitians to support Australia's elite collision sport athletes, new Griffith University research has found. Lead author Dr. Nathan Delang…