Current reporting, research and professional developments across Neuropsychology, curated for psychologists and behavioral-health professionals.
Despite global efforts to develop disease-modifying therapies for Parkinson’s disease (PD), recurrent trial failures persist, likely driven by profound and unstratified molecular heterogeneity. The advent of α-syn seed…
Achieving intuitive neural control of supernumerary robotic limbs remains a major challenge in human movement augmentation. Although brain-machine interfaces (BMIs) can translate motor imagery (MI) into robotic commands…
Friedreichâs ataxia (FA) is a mitochondrial disease caused by frataxin deficiency that leads to progressive neurodegeneration and cardiomyopathy. Effective disease-modifying therapies remain limited. Here we show that…
Activation of microglia is a prominent feature of amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that leads to the death of motor neurons. A key component of this activation is elevated expression of…
NASA has a robust history of biomedical investigations using rodent models in spaceflight. The results from these experiments have provided significant insights into the effects of spaceflight on mammalian physiological…
Postpartum depression (PPD) is among the most common complications of childbirth, and identifying novel treatments is vital. We aimed to identify potential drug targets for PPD by integrating the plasma proteome…
Parkinson’s disease (PD) is a heterogeneous neurodegenerative disorder with variable long-term outcomes. Blood-based biomarkers for prognostic prediction remain underdeveloped. We aimed to develop a peripheral blood…
Electroconvulsive therapy (ECT) is effective for treating depression. Recent studies suggest that ECT can induce cortical spreading depression (CSD), which may have clinical benefits. However, the probability of CSD…
Early regulatory problems (RPs, i.e. problems with crying, sleeping and feeding), are associated with increased susceptibility to avoidant personality traits and peer relationship issues in adulthood. RPs have been…
We present and validate a pioneering ‘IHC/LCM-Seq’ method for transcriptome profiling of spatially defined neuronal cell types detected with immunohistochemistry in sections of formaldehyde-fixed human brains…
Microglia are central regulators of retinal immune homeostasis, yet their pathogenic states in retinal degeneration remain less well understood. Here we identified a distinct subset of lipid-accumulated reactive…
Drosophila olfactory sensory neurons tend to express a single ligand-specific receptor, following a one-receptor-per-neuron rule expected to apply broadly across insects. Recent work challenges this view by showing that…
Preterm birth disrupts early brain development, increasing the risk of cognitive difficulties. However, its long-term effects on functional brain network energy, a metric of large-scale network stability and…
Abundant evidence shows that when listening to speech or reading text, we continuously make high-level predictions about upcoming words â their content, meaning, and relationship to the overall narrative. Does this…
Visual food stimuli are widely used in food perception and evaluation research, but are often limited by a lack of control of confounding variables. AI-generated food images may be a viable but yet understudied…
Researchers discovered that the youth-associated protein TIMP2 restores healthy immune function in the aging brain by rejuvenating microglia.
For centuries, scholars have read ancient documents describing the production of brass in 10th-century A.D. China. The problem was that the earliest physical evidence of brass production would be found nearly 600 years…
New genetic analyses of ancient human skeletons from western Remote Oceania are shedding light on the complex history of settlement in this vast Pacific region over the past 3,000 years. With island nations such as…
Brain stimulation can produce very different effects at different moments, even when the stimulus is delivered exactly the same way. A new study published in Brain Stimulation shows that the brain's ongoing activity…
Foods and drinks linked to higher Alzheimer’s and dementia risk in older adults center on ultra-processed items, sugary beverages, processed meats, excess saturated fats, and alcohol. Emerging ...
Singing in a neurological choir – a singing group designed for individuals living with acquired brain injuries and neurodegenerative disorders – reduces social isolation and the sense of loss that ...
A medieval monastery complex, long believed to be lost, has now been identified using ground-penetrating radar (GPR) in Roskilde, Denmark. The investigations have uncovered extensive and well-preserved remains of the St…
The Huashan rock art landscape in southern China, close to the border with Vietnam, is a remarkable UNESCO World Heritage site. Thousands of images are painted on river cliffs across more than 80 locations stretching 260…
Scientists have discovered that the aging human brain may be far less isolated from the rest of the body than once believed. Stanford researchers found that large numbers of immune cells from the blood begin entering the…
A Stanford study found estrogen-only menopausal hormone therapy linked to 35% lower Alzheimer's pathology and 39% lower dementia odds in women.
Latin squares are arrangements of symbols in a grid in which every symbol appears exactly once in each row and column. These symbol arrangements, which were first studied more than three centuries ago, are now widely…
Women who used estrogen-only hormone therapy later in life were less likely to develop dementia and showed fewer signs of Alzheimer’s disease in their brains, according to a large study of more than 21,000 participants…
Meteorites provided a rare but ready source of iron for ancient Bronze Age cultures before smelting became common. A new study, published in the Journal of Archaeological Science, sheds light on how the ancient Minoan…
AbbVie’s ABBV neuroscience franchise continued to deliver strong growth in the first half of 2026, with sales reaching $6.1 billion, up 21.8% year over year on an operational basis. While the segment ...
More than 7 million people in the United States have Alzheimer's, and the number of people aged 65 or older with the disease could exceed 13 million by 2050.
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