Current reporting, research and professional developments across Neuropsychology, curated for psychologists and behavioral-health professionals.
Diphenhydramine, the active ingredient in Benadryl and in most over-the-counter nighttime sleep aids, is one of the most familiar drugs in the medicine cabinet. It is a first-generation antihistamine, ...
Key Takeaways Healthy habits in middle age can significantly reduce dementia riskNormal blood pressure, no diabetes and no smoking lead to about 13 years longer without dementiaResearchers conclude ...
Growing older does not automatically mean losing memories. While age remains the biggest risk factor for dementia, scientists are learning that the story begins much earlier than most people imagine.A ...
Taxi and ambulance drivers are less likely than workers in almost any other job to die of Alzheimer's disease.
Aging is the single biggest risk factor for neurodegenerative diseases like Alzheimer's, but scientists still have plenty of questions about what happens inside the brain as the years go by. That's ...
The three things you can do in middle age ‘to hold off dementia’, according to the experts - Those who had none of the three risk factors in the study lived without developing dementia nearly 13 years ...
Further strengthening its technological credentials, IQED has been selected as part of NVIDIA's prestigious Inception Program, through which the company has received technology investment credits of ...
Ephaptic coupling can modify spike timing in closely packed myelinated axons, but its effect on physiologically relevant spike patterns remains unexplored. In this study, we used a biophysically detailed model of…
Social Laser Theory (SLT) provides an innovative quantum-like mathematical formalism for tracking complex collective social activation dynamics. While its macroscopic manifestations structurally mimic laser physics, the…
Coping factors, such as perceived or actual behavioral control over some aspect of an adverse event, are associated with resilience and are often argued to help optimize or even dampen glucocorticoid responses to…
We identify hallucination in AI models of fluid dynamics using the canonical problem of hydrodynamically unstable transport known as viscous fingering. AI-based modeling of flow with instabilities remains challenging…
Premature epigenetic aging has been linked to poorer cognitive performance, but the neuroanatomical pathways underlying this association remain unclear. Therefore, we tested whether premature epigenetic aging predicts…
The estimated glucose disposal rate (eGDR) is associated with the incidence of incident stroke (IS). However, its role in predicting IS within the Circadian Syndrome (CircS), a multisystem metabolic disorder, remains…
Opioid use disorder remains a health crisis with high risk of relapse and mortality, and new therapeutic options beyond the current standard of care are needed. Here, we present results from a pilot cohort of an opioid…
Nicotinamide has demonstrated pain-relieving effectiveness in osteoarthritis (OA) patients. However, there are no data on the mechanism of its analgesic effect. We aimed to examine the behavioral/cardiac effects of…
Tracking and analyzing animal behaviour is a crucial step in fields such as neuroscience and developmental biology. Behavioural studies in the nematode C. elegans, for example, help in understanding how organisms respond…
Dopamine (DA) is a key modulator of prefrontal cortex function, yet how distinct dopaminergic states shape the temporal organization of cortical population activity during behavior remains poorly understood. We combined…
The circadian clock is present throughout the body, including the intestine, where it regulates daily physiology through rhythmic gene expression. The large intestine (colon) is composed of many functionally distinct…
For more than half a century, glaucoma management has relied on a single number: the value of intraocular pressure (IOP) [1]. However, the value we consider with such confidence is not one we ever directly measure! In…
Retinal degeneration results in irreversible visual impairment. In a neurodegenerative animal model, xanthine oxidoreductase inhibitor application reduced disease severity. The present study examined the effect of a…
Astrocyte-derived protein, S100B exerts neurotrophic and neuroprotective effects at physiological concentrations but may promote neuroinflammation and damage when dysregulated. Given its potential role in the…
Psychedelic drugs, such as lysergic acid diethylamide and psilocybin, have emerged as potentially transformative therapeutics for various neuropsychiatric conditions, including depression, anxiety, post-traumatic stress…
The insular cortex has become an increasingly important focus of neuroscientific research because of its broad involvement in psychological and behavioral processes and its dysfunction in neuropsychiatric, developmental…
Glioma pathophysiology is robustly regulated by interactions with neurons. Key to these interactions is the role of neuroligin-3 (NLGN3), a synaptic adhesion molecule shed in response to neuronal activity that functions…
Comorbid depressive symptoms are highly prevalent in patients with chronic colitis, posing a major clinical challenge because pain and depression often fail to respond to the same treatment. However, the neural…
The initiation and maintenance of pain involves complex neuroimmune interactions, with myeloid cell output finetuning the balance between pronociceptive and antinociceptive signaling. Fatty acid binding protein 5 (FABP5)…
Hearing loss is a major modifiable risk factor for cognitive decline and dementia in older adults. This prospective cohort study evaluated five-year cognitive trajectories in individuals aged ≥ 55 years with bilateral…
At Duke University, Sharon Gerechtâs group wanted to construct an in vitro model to study the iBRB. For reproducibility, they needed a stable and consistent supply of both retinal pericytes (RPCs) and RECs. Protocols…
Aging is the most significant factor affecting an individual’s cognitive function. This study aimed to explore the association between light BioAge, a novel indicator to assess aging, and the risk of cognitive impairment…
A DNA tile consists of four double helices that stack together to form a pore with a diameter of 0.8 nanometers. When modified with cholesterol, they can anchor into membranes and mimic ion channels. Jayant says that…
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