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Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceThe bladder is innervated by complex sensory networks, yet the specific role of stretch-insensitive mucosal nerves has…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceVoltage-gated calcium channels regulate critical physiological processes, and some genetic variants inCACNA1Dcan cause…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceStudies have demonstrated that adoptive cell transfer with antitumor CD4+T cells can be effective in treating advanced stage…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceSevere hand, foot, and mouth disease caused by Enterovirus 71 (EV-A71) threatens global pediatric health, yet its infection…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceAn HIV-1 cure strategy will require novel therapeutics to facilitate immune-mediated elimination of infected cells and…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceIt remains unclear whether developmental transcription factors sustain adult cochlear function. We show that SIX1, known for…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceAnimals respond to injury, infection, or toxic materials via a process called inflammation. At the molecular level…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceOsteoarthritis (OA) is a major cause of pain and disability, yet no approved disease-modifying therapy can halt its…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceThe treatment of hepatocellular carcinoma (HCC) remains challenging, highlighting an urgent need for novel therapeutic…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceMetal oxide transistors are important building blocks for large-area, high-resolution displays due to their high carrier…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceOral cavity squamous cell carcinoma (OCSCC) is a deadly form of head and neck cancer that disproportionately afflicts…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceManaging a pandemic requires balancing competing costs: interventions such as mask mandates and lockdowns reduce infections…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceEvolutionary dynamics selects more fit phenotypes over others. But fitness landscapes are complex and high dimensional, with…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceThe Hawaiian honeycreeper clade is a pre-eminent example of both adaptive radiation and human-mediated rapid extinction. We…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceAlthough human brain aging is not uniform across cortical regions, most imaging-derived measures of brain age quantify this…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceGlacial erosion rates vary over many orders of magnitude, but there are numerous hypotheses predicting the variables that…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceIn one of the largest prospective pregnancy cohorts with exposome phenotyping, we establish a prenatal…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceHow can the relationships between all known proteins be represented? Recent advances in AI describe proteins as vectors…
Proceedings of the National Academy of Sciences, Volume 123, Issue 32, August 2026. SignificanceForest regeneration is widely promoted as a strategy to restore ecosystem services in the Amazon, yet whether regenerating…
Washington, D.C. — The latest issues of three American Psychiatric Association journals (The American Journal of Psychiatry, Psychiatric Services, and Focus) are now available online. The August issue of The American…
Behind each article we publish stands a team of superheroes: authors, editors, and reviewers who chose to uphold quality standards and share knowledge openly. Read more about the impact your work achieves. Volume 20…
Nature Human Behaviour, Published online: 03 August 2026; doi:10.1038/s41562-026-02522-4Analysing data from 5,227 students from northern Italy, this article finds causal evidence that early engagement with social media…
Nature Human Behaviour, Published online: 03 August 2026; doi:10.1038/s41562-026-02523-3A longitudinal study of Italian students revealed a significant negative effect of early use of social media on later academic…
Interventions such as cognitive behavioral therapy can improve mental health for cancer patients and increase survival.
Greater disease severity, pruritus-related sleep disruption, and chronicity correlated with worse anxiety/depression and health ...
If you're struggling with alcoholism, ayurveda offers natural, holistic remedies—like ajwain decoction, soothing herbs, and mindful nutrition—to help reduce cravings, support detoxification, and ...
Former rugby player Phil Vickery recently announced that he has pledged to donate his brain to help advance concussion research.
Researchers tracking the sleep of men and women in the U.K. between the ages of 50 and 66 found nearly 70% experienced persistent sleep problems, and many may be linked closely to work-related stress.
AI is not a future technology. It is already embedded in the products, platforms, and systems LGBTQ people use every day." ...
An HIV diagnosis can bring fear, stigma, isolation and uncertainty. For some people, these pressures can contribute to depression, while depression can make it harder to stay in care, take medication ...
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