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Co-expression of tau and amyloid-beta with α-syn pathology is shown in over 50% of Parkinsonâs Disease postmortem brains, and these patients present with enhanced cognitive decline and disease phenotype. This review…
Download the Nature Briefing Podcast 14 August 2026 Nature: Can Anthropicâs invisible watermarks curb âAI slopâ? Researchers remain sceptical Nature: Where are you ticklish? Researchers map the sensation across…
Cognitive impairment affects 30%â80% of patients with heart failure, yet the mechanisms beyond reduced brain blood flow remain poorly defined. Here we show that circulating factors released during heart failure trigger…
Perceptual judgements and their metacognitive evaluation are considered tightly coupled aspects of decision-making, yet emerging evidence suggests distinct neural mechanisms underlie these processes. In motion…
Whether the brain encodes the subjective value of pleasant and unpleasant situations via a single integrated circuit or through distinct pathways remains unresolved. How such signals guide choice across contexts also…
Irritable bowel syndrome (IBS) is increasingly recognised as being associated with distributed structural and functional brain alterations, yet existing neuroimaging syntheses lack an integrated multimodal approach…
Creating captivating museum experiences is crucial, yet understanding how these experiences influence visitors remains limited. This study investigates the influence of holographic displays on visitor engagement and…
Cognitive screening tools are rarely validated for Indigenous populations of Latin America, a barrier to early dementia detection. We culturally adapted and evaluated the psychometric performance of the Peruvian version…
Depression and anxiety are common mental health disorders that often share overlapping symptoms. This can limit the specificity of standard screening tools and complicate differential diagnosis. Changes in judgment can…
Human interaction invariably occurs within a specific context. Although recent research highlights the role of context for emotion communication, the specific influence of the environmental ambience (the settingâs…
Changes in personality during adolescence may shape future alcohol use, especially in times of societal crisis. The COVID-19 pandemic disrupted social norms and stress regulation, making it a natural experiment to…
With the advancement of digital education, short videos have emerged as a powerful teaching and learning, demonstrating unprecedented potential for education for sustainable development (ESD). This study examines how…
Drink spiking has received increasing public and media interest in the United Kingdom (UK), particularly following reports of needle spiking in 2021. Despite growing concern, incidents remain under-reported due to…
Major Depressive Disorder (MDD) is a common and costly mental health condition that is often associated with deficits in executive function. Smartphone applications (“apps”) have emerged as promising methods for…
Reinforcement learning from human feedback and related preference-tuning methods are widely used to make large language models safer, yet repeated tuning may also alter the boundary between refusal and compliance…
Accurate assessment of reading comprehension difficulty represents a fundamental challenge in adaptive learning systems and educational content development. Traditional readability formulas rely on surface-level…
Cognitive-motor interventions may help preserve and enhance cognitive, physical and sensorimotor function in aging populations, however, their feasibility for older adults working in cognitively demanding positions and…
This study aimed to assess factors associated with natural SARS-CoV-2 infection among undiagnosed Singaporean adults in the late stage of the pandemic. Snowball sampling was used to recruit a convenient sample of adults…
This article presents a case-based ethical analysis of a critically ill COVID-19 patient in an ICU in mainland China, focusing on the conflict between a previously expressed refusal of life-sustaining treatment and…
This study examines the association between executive military experience and corporate environmental, social, and governance (ESG) performance. Using a sample of Chinese A-share listed firms from 2010 to 2023, we find…
Could the design of a spacecraft affect astronauts’ mental health? Scientists have mapped how everything from lighting and privacy to shared spaces could shape wellbeing on long missions to the Moon ...
Nepal, Aug. 14 -- Last Spring, I was in Sydney, Australia, working on my research project and carrying my dream of permanently residing in the country. After decades of professional research and ...
Hospitals across the U.S. are trying to reduce maternal deaths and complications after pregnancies using one small tool: a silicone wristband stamped with the declaration "I Gave Birth."
Difficult childhood experiences shape lifelong attachment patterns, making extreme independence feel safer than relying on others. While that mindset can foster resilience and self-reliance, it can ...
Imagine heading to a doctor's office for memory problems and getting a prescription to hang out with friends.
The proportion of women with early breast cancer who receive chemotherapy varies significantly across different regions of Sweden. A study from Karolinska Institutet, published in the journal Breast Cancer Research…
More than a decade ago, Dr. Matthew Hebb was treating patients with Parkinson's disease using deep brain stimulation by implanting tiny electrodes into the brain and delivering electrical signals to control tremors. He…
With temperatures forecast to reach around 37°C (99°F) in places, reaching for an ice cream or an icy drink might seem like an excellent idea. There is, however, one small hazard to eating your frozen treat with too much…
A new study reveals that daily doses of psilocin mucate, a stable derivative of the psychedelic compound psilocybin, significantly reduced anxiety and stress hormones in rats. However, weekly dosing did not produce the…
Researchers at Baylor College of Medicine and Texas Children's Hospital have uncovered an intervention that could potentially improve outcomes for children with malnutrition, a condition that contributes to nearly half…
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